Inflammation Rx

Name: Inflammation Rx
SKU: 4889-C247-60
Price: 49.99 USD
Availability: OutOfStock
Rating: 4.92 (66 reviews)

Rated 4.92 out of 5 based on 66 customer ratings

(66 customer reviews)

$49.99

Out of stock

NATURAL ANTI-INFLAMMATORY

#1 Doctor Recommended
Enhance Immunity, Joint Health & Digestion/Absorption
Synergistic Ingredients Supported By More Than 65 Studies
Prescription Grade, Fast Acting
VEGAN, NON-GMO, SOY & GLUTEN FREE

SKU: 4889-C247-60 Category: Inflammation

Additional information

Amount	60 capsules

Supplement Facts

Serving Size: 2 capsules Servings Per Container: 30

Active Ingredients	Amt/Serving	% DV
IMMUNITY MATRIX
Vitamin C (as absorbic acid)	150 mg	167%
Zinc (as zinc amino acid chelate)	5 mg	45%
ANTI-INFLAMMATORY MATRIX
Selenium (as selenium aspartate)	55 mcg	100%
Kre-Celazine® (Kre-Alkalyn® bonded to esterified fatty acids)	500 mg	✝
Turmeric extract (Standardized to 90% curcuminoids)	325 mg	✝
Ginger root powder	50 mg	✝
Bromelain	25 mg	✝
ABSORPTION MATRIX
Bioperine® (black pepper extract)	20 mg	✝

✝ Percent Daily Value "DV" Not Established.

OTHER INGREDIENTS: Capsule (vegetable cellulose), maltodextrin, magnesium stearate and silicon dioxide.

Product Label

Directions

SUGGESTED USE: As a dietary supplement, take two (2) capsules daily before a meal with water.

Ingredients

55mcg Selenium

SELENIUM FACTS

Selenium (Se) is a trace mineral with a role in multiple biologic functions through the activation of glutathione peroxidase, which plays a crucial role in antioxidant defense.
Exerts its anti-inflammatory effect through its protection against endoplasmic reticulum stress and down regulation of pro-inflammatory cytokine release.
Selenium has also been shown to demonstrate the ability to protect cartilage tissue in patients with KBD (Kashin-Beck disease) degenerative osteoarthritis.
Seafood, kidney, liver, yeast and nuts (especially Brazil nuts) are good sources of selenium.
Selenium deficiency is associated with skeletal muscle dysfunction, cardiomyopathy, mood disorders and impaired immune function.
Impaired cell-mediated immunity has been demonstrated when tissue stores of selenium are depleted.
Natural killer cell activity is enhanced when selenium is supplemented in the diet of selenium depleted individuals.
Selenium supplementation may decrease inflammatory activity in patients with autoimmune thyroiditis.
More studies need to be done on the link of selenium and reduction in pain and joint inflammation in people with rheumatoid arthritis.
The RDA (recommended dietary allowance) of selenium is 55 micrograms/day with tolerable upper intake limit of 400 micrograms/day.
In a double-blind study, bioavailability of selenium was evaluated alone and in combination with BioPerine®.
The serum selenium levels were approximately 30% higher in the group receiving selenium with BioPerine® after 2 weeks of treatment with a plateau in the subsequent time-points tested, working synergerically with Joint Edge Rx’s BioPerine.
The serum selenium levels were within normal limits in both groups at all time-points tested.

500mg Kre-Celazine®

KRE-CELAZINE® FACTS

- Kre-Celazine® is a “non-drug” patented ingredient that has been clinically shown to help reduce pain and promote joint flexibility and mobility along with reducing inflammation.
- Kre-Celazine® is a complex material consisting of bonding Kre-Alkalyn® (US Patent 6,399,661) with esterified fatty acid carbons.
  - The esterifying process makes the fatty acid stable so it does not react with oxygen. (This is not esterified creatine, the fatty acids have been esterified).
- Kre-Celazine® was granted Orphan Drug status in the treatment of Juvenile Idiopathic Arthritis by the FDA in 2013.
- Juvenile Idiopathic Arthritis (JIA) is a complex, chronic childhood autoimmune inflammatory disease.
  - Like rheumatoid arthritis in adults, joint and soft tissue destruction is relentless, except that this inflammation can begin when the patient is as young as a one-year old infant.
- In the clinical study published by LIEBERT, participants (ranging 7 to 17 years , who had been suffering from longstanding JIA, despite their use of chronic anti-inflammatory prescription medication) received two 750 mg capsules (total, 1,500 mg) of Kre-Celazine® to be taken daily for a period of 30 consecutive days. These patients experienced:
  (a) significant reduction or elimination of palpable inflammation
  (b) renormalization of range of motion
  (c) reduction/absence of perceived pain
  (d) renormalization of blood values for C-reactive protein and Erythrocyte Sedimentation rate.
- Based on the study results reported above, as well as those of a previous study published by JANA (Journal of the American Nutraceutical Association) using arthritic adults (Golini J, et al. 2009), Kre-Celazine® is a moderately effective non-prescription drug for the reduction of pain and stiffness of the extremities, neck, knee and shoulder regions in humans.
- Kre-Celazine® delivers a quad core of critical mechanism factors.
  - Core Factor 1: Supports Cellular Integrity.
    - Kre-Celazine® supports the integrity of cellular membranes to enhance their function with a precision blend of specialized lipids.This enables cell membranes to better repel stressors and offer greater cellular protection.
  - Core Factor 2: Reduces Inflammation
    - Plays a role in suppressing inflammation by reducing COX-2 enzyme, by inhibiting pro-inflammatory arachidonic acid and by helping to reduce the production of the inflammatory signaling Interleukin 6 molecule.
  - Core Factor 3: Restore and Support Optimal pH
    - The alkalizing power of Kre-Celazine® helps get your body working in a state that may be likened to a “greenhouse effect.”
    - This is a pH where your body’s cells and biological systems work in perfect harmony to function, grow, and recover optimally.
  - Core Factor 4: Support Muscle Energy and Strength
    - Kre-Celazine® features Kre-Alkalyn® (US Patent 6,399,661), a premium form of alkalinized pH-stable and soluble creatine.
    - Supplemental creatine, like Kre-Alkalyn®, may boost the muscles’ stores of creatine. In turn, this may allow for greater exercise potential and muscle stimulation that can strengthen muscles, like those around joints.

References

Ameye LG, Chee WS. Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence. Arthritis Res Ther. 2006; 8(4):R127.And at www.arthritis-research.com/content/8/4/R127Pages 1-22. [Accessed on 10-1-2008]
Buford TW, Kreider RB, Stout JR, Greenwood M, Campbell B, Spano M, Ziegenfuss T, Lopez H, Landis J, Antonio J. International Society of Sports Nutrition position stand: creatine supplementation and exercise. Journal of the International Society of Sports Nutrition 2007, 4:6 doi:10.1186/15502783-4-6.
Cassidy JT, Petty RE: Introduction to the Study of Rheumatic Diseases in Children. In Textbook of Pediatric Rheumatology – 5th Ed. Philadelphia: WB Saunders Company 2005:2–8. 5. Johnson K: Imaging of juvenile idiopathic arthritis. Pediatr Radiol 2006;36:743–758.
Curtis JL, Wolber FM, Sonstein J, Craig RA, Polak T, Knibbs RN, et al.: Lymphocyte-endothelial cell adhesive interactions in lung immunity: lessons from the murine response to particulate antigen. Immunopharmacology 2000;48:223–229.
Golini J, Beeson M, ND, Angersbach D, ND, Moore J, ND, Holl P, DC, Amicone C, ND, Jones W. A Single-Center, Double-Blind Placebo Controlled Study to Evaluate the Efficacy of Kre-Celazine®, an Oral Buffered Creatine-Cetylated Fatty Acid Compound, in its Ability to Reduce Site-specific Inflammation and Pain. JANA. Vol. 12, No. 1, 2009: 20-25. ISSN-1521-4524. [www.ana-jana.org]
Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R: Cetylated fatty acids improve knee function in patients with osteoarthritis. J Rheumatol 2002;29:1708–1712.
Kraemer WJ, Ratamess NA, Anderson JM, et al. Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis. J Rheumatol. 2004; 31(4):767-774.
Kremer JM: n-3 fatty acid supplements in rheumatoid arthritis. Am J Clin Nutr 2000;71:349S–351S.
Lawrence RC, Felson DT, Helmick CG, et al. National Arthritis Data Workgroup. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 2008; 58(1):26-35.
Morelli V, Naquin C, Weaver V. Alternative therapies for traditional disease states: osteoarthritis. Am Fam Physician. 2003; 15:67(2):339-344.
Nomura A, Zhang M, Sakamoto T, Ishii Y, Morishima Y, Mochizuki M, et al.: Anti-inﬂammatory activity of creatine supplementation in endothelial cells in vitro. Br J Pharmacol 2003;139:715–720.
O’Connor RS, Steeds CM, Wiseman RW, Pavlath GK. Phosphocreatine as an energy source for actin cytoskeletal rearrangements during myoblast fusion. J Physiol. 2008; 15;586(Pt 12):2841-2853.
Silver FH, Bradica G, Tria A. Relationship among biomechanical, biochemical, and cellular changes associated with osteoarthritis. Rev Biomed Eng. 2001; 29(4):373-379.
Wang D, DuBois RN: An inﬂammatory mediator, prostaglandin E2, in colorectal cancer. Cancer J 2013;19:502–510.

325mg Turmeric

TURMERIC FACTS

Curcumin is the natural active extract found in the turmeric plant and the yellow pigment found in curry spice.
- It has been used therapeutically in Chinese medicine for thousands of years.
Research has shown that curcumin has powerful anti-oxidant and anti-inflammatory proprieties.
Curcumin has anti-inflammatory properties by inhibiting the major inflammatory pathway (Tnf-α and nF-kB) and the ability to mimic aspirin as a COX2 inhibitor.
Supplements containing curcumin reduce the severity of joint pain in individuals with osteoarthritis and even in those with rheumatoid arthritis.
Studies have shown that curcumin inhibits protein degradation after injury and in cases of cachexia (general wasting usually associated with chronic illnesses).
Curcumin supplementation following eccentric exercise led to reduced post-exercise inflammation and markers of muscle damage while also improving exercise recovery.
Over 200 studies have appeared demonstrating curcumin's cancer-preventive effects.
Curcumin activates PPAR (peroxisome proliferator-activator receptor), which is a group of key nuclear proteins that regulate gene expression and modulate sugar uptake and utilization in the bloodstream, modulating blood sugar and increasing insulin sensitivity, working synergistically with LionEdge’s Insulin Activation Matrix.
Bioavailability of Curcumin when co-administered with 20mg BioPerine was enhanced by 20-fold or 2000% compared to bioavailability of Curcumin alone.

References

Bharat B. Aggarwal, Chitra Sundaram, Nikita Malani, and Haruyo Ichikawa. Curcumin: The Indian Solid Gold. Advances in Experimental Medicine and Biology 595 (2007): 1–75.
Deng YT, Chang TW, Lee MS, Lin JK. Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells. J Agric Food Chem. 2012 Feb 1;60(4):1059-66.
Sita Aggarwal, Haruyo Ichikawa, Yasunari Takada, Santosh K. Sandur, Shishir Shishodia, and Bharat B. Aggarwal. Curcumin (Diferuloylmethane) Down-Regulates Expression of Cell Proliferation and Antiapoptotic and Metastatic Gene Products through Suppression of IκBα Kinase and Akt Activation. Molecular Pharmacology 69, no. 1 (2006): 195–206. doi: 10.1124/mol.105.017400.
Li YP, Chen Y, John J, Moylan J, Jin B, Mann DL, Reid MB. TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle. FASEB J. 2005 Mar;19(3):362-70.
Deepa Thaloor, Kristy J. Miller , Jonathan Gephart , Patrick O. Mitchell , Grace K. Pavlath. Systemic administration of the NF-κB inhibitor curcumin stimulates muscle regeneration after traumatic injury. American Journal of Physiology - Cell PhysiologPublished 1 August 1999, Vol. 277no. C320-C32.
Preetha Anand, Ajaikumar B. Kunnumakkara, Robert A. Newman, and Bharat B. Aggarwal, Bioavailability of Curcumin: Problems and Promises. Molecular Pharmaceutics 4, no. 6 (2007): 807–18. doI: 10.1021/mp700113r.
Guido Shoba, David Joy, Thangam Joseph, Muhammed Majeed, Rajesh Rajendran, and Priya S. S. R. Srinivas. Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers.Pharmacology 64, no. 4 (1998): 353–56. doi: 10.1055/s-2006-957450.
Chainani-Wu N. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). J Altern Complement Med. 2003 Feb;9(1):161-8.
R.R. Kulkarnia, P.S. Patkia, V.P. Joga, S.G. Gandagea, Bhushan Patwardhan Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.
Chandran B, Goel A. A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis. Phytother Res. 2012 Nov;26(11):1719-25.
G.K. Jayaprakasha, L. Jaganmohan Rao, K.K. Sakariah. Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin. Food Chemistry. Volume 98, Issue 4, 2006, 720-724.

50mg Ginger

GINGER FACTS

The spice ginger is the natural underground rhizome of the ginger plant, known botanically as Zingiber officinale, used in many countries as a spice and condiment to add flavor to food.
Ginger has a very potent anti-inflammatory effect which has been shown to reduce muscle pain after intense physical activity.
During the past 40 years, many studies have provided scientific support for the long-held belief that ginger contains potent anti-inflammatory properties; the original discovery of ginger's inhibitory effects on prostaglandin biosynthesis in the early 1970s has been repeatedly confirmed.
Ginger suppresses prostaglandin synthesis through inhibition of cyclooxygenase-1, cyclooxygenase-2 and 5-lipoxygenase.
A University of Miami study compared the effects of ginger extract to placebo in 247 patients with osteoarthritis (OA) of the knee. The ginger reduced pain and stiffness in knee joints by 40 percent over the placebo.
Researchers at the University of Georgia in Athens and Georgia State College & University in Milledgeville reported in the Journal of Pain that a few tablespoons of grated ginger can help ease muscle pain caused by exercise.
If the anti-inflammatory properties of ginger mentioned above aren’t enough, ginger also has insulinoptropic properties through the 5-HT3 receptor channel, increasing plasma insulin secretion up to 10%, working synergistically with LionEdge’s Insulin Activation Anabolic Matrix.
Ginger has staring potential for treating a number of ailments including degenerative disorders (arthritis and rheumatism), digestive health (indigestion, constipation and ulcer), cardiovascular disorders (atherosclerosis and hypertension), vomiting, diabetes mellitus, and cancer.
- It also has anti-inflammatory and anti-oxidative properties for controlling the process of aging.
References
1. Phan PV, Sohrabi A, Polotsky A, Hungerford DS, Lindmark L, Frondoza CG. Ginger extract components suppress induction of chemokine expression in human synoviocytes. J Altern Complement Med. 2005 Feb;11(1):149-54. 2005.
2. Jagetia GC, Baliga MS, Venkatesh P, Ulloor JN. Influence of ginger rhizome (Zingiber officinale Rosc) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation. Radiat Res. 2003 Nov;160(5):584-92. 2003.
3. Kiuchi F, et al. Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids. Chem Pharm Bull 40 (1992):387-91. 1992.
4. Srivastava KC, Mustafa T. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypothesis 39(1992):342-8. 1992.
5. Wigler I, Grotto I, Caspi D, Yaron M. The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarthritis Cartilage. 2003 Nov;11(11):783-9. 2003.
6. Terry R, Posadzki P, Watson LK, Ernst E. The use of ginger for the treatment of pain: a systematic review of clinical trials. Pain Med. 2011 Dec;12(12):1808-18.
7. 7. Nammi S, Sreemantula S, Roufogalis BD. Protective effects of ethanolic extract of Zingiber officinale rhizome on the development of metabolic syndrome in high-fat diet-fed rats. Basic Clin Pharmacol Toxicol. 2009;104:366–73.
8. Heimes K, Feistel B, Verspohl EJ. Impact of the 5-HT receptor channel system for insulin secretion and interaction of ginger extracts. Eur J Pharmacol. 2009;624:58–65.
9. Dugasani S, Pichika MR, Nadarajah VD, Balijepalli MK, Tandra S, Korlakunta JN. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol. J Ethnopharmacol. 2010;127:515–20.
10. Ohshima H, Tatemicho M, Sawa T. Chemical basis of inflammation-induced carcinogenesis. Arch Biochem Biophys. 2003;417:3–11.
11. Ramaa CS, Shirode AR, Mundada AS, Kadam VJ. Nutraceuticals an emerging era in the treatment and prevention of cardiovascular diseases. Curr Pharm Biotechnol. 2006;7:15–23.

25mg Bromelain

BROMELAIN FACTS

Bromelain belongs to a group of natural protein digesting enzymes obtained from the fruit or stem of pineapple.
Research has shown that bromelain has anti-inflammatory and analgesic properties
Bromelain's action as an anti-inflammatory is mediated via the following factors: reducing plasma fibrinogen levels, decreasing bradykinin levels (which results in reduced vascular permeability and hence reducing edema and pain), decreasing levels of PGE₂ and thromboxane.
Bromelain was first reported to be of value as an analgesic and anti-inflammatory for use in both rheumatoid arthritis and osteoarthritic patients in 1964.
Ten studies have been identified that have assessed bromelain in osteoarthritis of the knee, most of which indicated that the use of bromelain had positive clinical effects (as measured by assessment of reduction in soft tissue swelling, pain and/or joint stiffness) and no adverse events associated with the medication were reported in any of these case reports.
In a blinded study from Germany, researchers divided 90 patients with painful osteoarthritis of the hip into two groups: one half receiving bromelain for six weeks, while the other half received the anti-inflammatory drug diclofenac. They found that the bromelain preparation was as effective as diclofenac in standard scales of pain, stiffness and physical function, and better tolerated than the drug comparator.
Bromelain helps break down and digest protein, working alongside LionEdge’s Absorption Enhancing Matrix.
Bromelain accounts for many therapeutic benefits including the treatment of angina pectoris, inflammatory bowel disease, sinusitis, surgical trauma, debridement of wounds, and enhanced absorption of drugs, particularly antibiotics.

References

Maurer HR. Bromelain: biochemistry, pharmacology and medical use. Cell Mol Life Sci. 2003 Aug;58(9):1234-45.
Brien S, Lewith G, Walker A, Hicks SM, Middleton D. Bromelain as a treatment for osteoarthritis: a review of clinical studies. Evid Based Complement Alternat Med. 2004 Dec;1(3):251-7.
Klein G, Kullich W, Schnitker J, Schwann H. Efficacy and tolerance of an oral enzyme combination in painful osteoarthritis of the hip. A double-blind, randomised study comparing oral enzymes with non-steroidal anti-inflammatory drugs. Clin Exp Rheumatol. 2006 Jan-Feb;24(1):25-30.
Akhtar NM, Naseer R, Farooqi AZ, Aziz W, Nazir M. Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee—a double-blind prospective randomized study. Clin Rheumatol. 2004 Oct;23(5):410-5.
Cohen A, Goldman J. Bromelain therapy in rheumatoid arthritis. Penn Med J. 1964;67:27–30.
Leipner J, Iten F, Saller R. Therapy with proteolytic enzymes in rheumatic disorders. Biodrugs. 2001;15:779–789.
Singer F, Oberleitner H. Drug therapy of activated arthrosis. On the effectiveness of an enzyme mixture versus diclofenac. Wien Med Wochenschr. 1996;146:55–58.
Klein G, Kullich W. Short-term treatment of painful osteoarthritis of the knee with oral enzymes: a randomised, double-blind study versus Diclofenac. Clin Drug Invest. 2000;19:15–23.
Singer F, Singer C, Oberleitner H. Phlyoenzym versus diclofenac in the treatment of activated osteoarthritis of the knee. Int J Immunother. 2001;17:135–141.
Tilwe GH, Beria S, Turakhia NH, Daftary GV, Schiess W. Efficacy and tolerability of oral enzyme therapy as compared to diclofenac in active osteoarthritis of the knee joint: an open randomized controlled clinical trial. Journal of the Association of Physicians of India. JAPI. 2001;49:621.
Walker AF, Bundy R, Hicks SM, Middleton RW. Bromelain reduces mild acute knee pain and improves well being in a dose dependant fashion in an open study of otherwise healthy adults. Phytomedicine. 2002;9:681–686.

20mg BioPerine®

BIOPERINE FACTS

BioPerine® is the only patented piperine which is extracted from black pepper.
The only source from piperine to have undergone several clinical studies in the U.S. to substantiate its safety and efficacy for nutritional use.
Gastrointestinal absorption of all the studied nutrients, as measured by amounts present in the blood, increased dramatically when administered with BioPerine^® as compared to the control group receiving the nutrient alone.
Research suggests it enhances nutrient digestion and absorption by increasing blood flow to the digestive tract through thermogenesis , thus significantly increasing bioavailiblity of the nutrients.
Bioperine® enhances amino acids, water-soluble and fat-soluble vitamins, anti-oxidants and minerals – all of which are included in Post-Edge™.
Bioavailability of Curcumin when co-administered with 20mg BioPerine was enhanced by 20-fold or 2000% compared to bioavailability of Curcumin alone.

References

Srinivasan, K. Black pepper and its pungent principle-piperine: a review of diverse physiological effects. Critical reviews in food science and nutrition. 2007; 47.8:735-748.
Brewer, M. S. Natural antioxidants: sources, compounds, mechanisms of action, and potential applications. Comprehensive Reviews in Food Science and Food Safety. 2011; 10.4:221-247.
Reanmongkol, Wantana, et al. Effects of piperine on bioenergetic functions of isolated rat liver mitochondria. Biochemical pharmacology. 1988; 37.4:753-757
Shoba, G, et al. Influence Of Piperine On The Pharmacokinetics Of Curcumin In Animals And Human Volunteers. Planta Med. 1998; 64(4):353-356.
Badmaev, V, et al. Piperine, An Alkaloid Derived From Black Pepper, Increases Serum Response Of Beta-Carotene During 14-Days Of Oral Beta-Carotene Supplementation. Nutrition Research. 1999; 19(3) 381-388.
Epstein, William W.; Netz, David F.; Seidel, Jimmy L. (1993). "Isolation of piperine from black pepper". J. Chem. Ed. 70 (7): 598.
Badmaev, V, et al. Piperine Derived From Black Pepper Increases The Plasma Levels Of Coenzyme Q10 Following Oral Supplementation. J. Nutr. Biochem. 2000; 11: 109-113

150mg Vitamin C

5mg Zinc

Add a review

66 reviews for Inflammation Rx

Rated 5 out of 5

Alexander L – May 18, 2022

I’ve been dealing with chronic gout for years and sometimes my joints and toes swell up like balloons during my flare ups. I’ve been taking prescription medicine for quite some time but decided to give this a try after hearing about it and reading all the positive reviews and getting an ok from my doctor to use it. I can say it worked wonders for me and have less pain and even swelling during my flare ups!
Rated 5 out of 5

Russell O – March 18, 2022

Worth every penny guys! HUGE difference when taking Inflammation Rx. At first I thought it was placebo but again noticed less joint aches and faster recovery times when I started using again.
Rated 5 out of 5

Maria B – March 6, 2022

Helps with my indigestion and especially my bloating which I usually have after my meals but since using inflammation rx i don’t have these issues anymore.
Rated 5 out of 5

Brenda C – February 3, 2022

Suffer from chronic knee pain in both knees for decades and I also have IBS. Ive tried almost everything and this product has really helped for both of these issues. I love that it’s all natural vegan and made by doctors. I even told my family doctor about it and she’s also referred it to some of her patients!
Rated 5 out of 5

Trevor A – January 16, 2022

Really helped with my shoulder pain from a bike injury I had months ago!
Rated 4 out of 5

Eugene V – January 9, 2022

Some improvement in my chronic joint aches with this product.
Rated 5 out of 5

Donald T – December 23, 2021

Third time ordering and still working great for my chronic knee pain and arthritis
Rated 5 out of 5

Gary W – December 19, 2021

Less joint pain since using Inflammation RX. At first I was convinced it was a placebo effect but I knew that wasn’t the case after I ran out of the pills..
Rated 5 out of 5

Janice F – December 13, 2021

Amazing product really helped with my tendinitis and works fast!!
Rated 5 out of 5

William A – December 7, 2021

Tried this product with the “immunity stack” after a work colleague told me about it. I’ve had arthritis for years and I’ve had less aches overall since using inflammation rx without the stomach upset I occasionally get from NSAIDS. Very satisfied
Rated 5 out of 5

Noah B – November 7, 2021

Huge difference since using inflammation rx. Went from chronic knee pain to running almost daily! I can really tell the difference when I don’t take this product.
Rated 5 out of 5

Jim S – October 30, 2021

Use this daily religiously and feel much better overall.
Rated 5 out of 5

Dawn J – August 2, 2021

My husband and I (in our late 60’s), both started taking this – taking one pill a day (half dose). My husband has been receiving shoulder injections every 6 mos. for inflammation/pain, etc. He actually was able to delay the next appt. We credit “Inflammation RX”. Our gut health seems more in check and we aren’t as stiff and achy when we wake up. Thank you LionEdge !!
Rated 5 out of 5

Sharon N – July 7, 2021

Great product. I like that all the ingredients and dosages are listed out and fully transparent. Have been using daily for the vitamin c and zinc immunity boost and knees feel a little better from the anti inflammatory herbals.
Rated 5 out of 5

Jill A – May 23, 2021

This product has really worked well for me I could tell within the first week. Less soreness after running and just feel better overall since I’ve started using
Rated 5 out of 5

Connie M – April 18, 2021

I’ve been ordering inflammation RX monthly for me and my husband it actually works as advertised for the both of us and will be lifelong customers!
Rated 5 out of 5

Sam V – April 14, 2021

Great product less joint pain and aches since starting with no side effects whatsoever
Rated 5 out of 5

Bill W – April 12, 2021

Have been feeling a lot better after my workouts since starting inflammation rx. I’ve even noticed less digestion issues. Being vegan is a plus too very pleased
Rated 5 out of 5

Kristin T – January 18, 2021

Phenomenal supplement! I could tell the difference after using inflammation rx. Less joint pain and could workout and run more than ever!
Rated 4 out of 5

Nicole P – December 6, 2020

Second run and haven’t gotten sick yet. Less aches and feel better overall since using
Rated 5 out of 5

Vicky C – November 25, 2020

Smoother digestion and less muscle and joint aches. Very pleased with this product!
Rated 5 out of 5

Tom L – October 29, 2020

Awesome product!! Like that the dosages are listed out and that it’s a vegan product. Could feel the difference in my back pain after I ran out of these pills. Just placed my order!
Rated 5 out of 5

Michelle B – October 24, 2020

Has become one of my go to daily regimes.. Not only for the immunity boost but I’ve noticeably have had less knee pains and bloating since starting this product.
Rated 5 out of 5

Raymond D – October 22, 2020

Inflammation Rx is the best natural anti-inflammatory I’ve ever tried!
Rated 5 out of 5

Sal R – October 17, 2020

Noticeably less knee and elbow pains. I’ve had arthritis and tendinitis for years and this product has been working very well for me. Nice to cut down the nsaids!
Rated 5 out of 5

Crystal T – October 14, 2020

Came with my stack and worked very well for me! Less pains and aches after my HIIT workouts and less gas issues since starting
Rated 5 out of 5

Erin K – October 14, 2020

Works as advertised. I’ve had less joint pain, especially after running since starting this product. Have also noticed less bloating. The immunity boost and the fact it’s vegan is a big plus too!
Rated 5 out of 5

Jacob Z – October 7, 2020

I don’t really have joint pain but was more interested in the Immunity and gut health benefits. I’ve noticed smoother digestion and less bloating since starting. will be trying the proteins next!
Rated 5 out of 5

Jess B – September 29, 2020

One of my favorite products from the stack. Not just because of the immunity benefits but helped with my recovery (I’m an avid runner with chronic knee pain) but my digestion seemed to be better as well! Also like the fact that all the ingredient dosages are on the label and it’s vegan!!
Rated 5 out of 5

Angela F – September 21, 2020

Could really feel the difference in my joints in just a few weeks. I just feel better overall while using this and will be ordering again
Rated 5 out of 5

Phil Y – December 29, 2019

Less joint Pain and stiffness since using.
Rated 5 out of 5

Jack B – December 10, 2019

Great product. Works as advertised and will continue to use for my joint pain
Rated 5 out of 5

Sally B – October 19, 2019

Been using this product for 3 months and feel a world of difference! I’m not having to use nsaids anymore and my joints have been feeling great!
Rated 4 out of 5

Ruth Z – October 11, 2019

Great product. Helped with my knee and wrist pains. Will continue to use
Rated 5 out of 5

Alex T – July 13, 2019

I’ve used quite a few joint supplements over the years and joint edge has worked the best by far. I could tell the difference in my usual aches in just days and it has continued to hellp!
Rated 5 out of 5

Brian T – April 23, 2019

Has been helping with my aches and able to push through my workouts longer, great product
Rated 5 out of 5

Jerry R – April 13, 2019

Worked great for me less knee pain and better recovery times after workouts
Rated 5 out of 5

Mary G – March 2, 2019

Has helped with my chronic aches and pains in my knees. No noticeable side effects. Will continue to use
Rated 5 out of 5

Max L – February 20, 2019

Definitely could feel a BIG difference before and after my workouts after starting joint edge. Soreness wasn’t as big of an issue and my body didn’t feel nearly as beat down after workouts.
Rated 5 out of 5

Greg C – February 16, 2019

This stuff really works!! Not only less joint pain but even improvement in my flexibility and overall strength. Very Impressed!
Rated 4 out of 5

Maggie P – January 27, 2019

I’ve been suffering with lupus for almost 15 years. Since starting joint edge, I haven’t had as much joint pain and swelling. Will keep using for now
Rated 5 out of 5

Ken B – January 18, 2019

Less knee and elbow pains. I just feel better overall since starting and even noticed less headaches and wife thinks better mood!
Rated 5 out of 5

Kristen F – January 7, 2019

On my third bottle and my friends who I told to use this also had great results. I stand behind this product!
Rated 5 out of 5

James L – December 13, 2018

Could feel a difference in my joint pain within just week of use and just felt better overall while using this product
Rated 5 out of 5

Kevin P – December 11, 2018

less inflammation and joint pain since starting great product!!
Rated 5 out of 5

Tim L – December 1, 2018

This Joint Edge RX is the real deal. I could feel a noticeable difference after using this product for a couple weeks, especially on my workout days!
Rated 5 out of 5

Benjamin W – November 25, 2018

I’ve had shitty painful joints for as long as I remember. I was very surprised with how well Joint Edge worked and it didn’t seem to wear off.
Rated 5 out of 5

Henry J – November 20, 2018

Could feel the difference in my joints in just a couple weeks. no side effects that I noticed. Will for sure continue to use.
Rated 5 out of 5

Jess M – November 17, 2018

Got the Joint Edge Rx with the Total Solution Stack. This stuff really works and it works fast! Impressive formula!
Rated 5 out of 5

Larry W – November 12, 2018

Faster Recovery, less joint pain and even better digestion. Phenomenal supplement!
Rated 5 out of 5

Max H – November 11, 2018

Big difference in my joint pains since starting Joint Edge. Legit ingredients and legit product!
Rated 5 out of 5

Megan L – October 13, 2018

I’m doing rehab for a torn meniscus and joint edge has worked wonders. I can tell a big difference from before and after starting the pills which means it actually works!
Rated 5 out of 5

Christian G – October 11, 2018

Noticeable difference in my knees and elbows in just a couple weeks. Very happy with the results
Rated 5 out of 5

Patrick L – October 5, 2018

I’ve had less pain and swelling in all of my problem joints since start joint edge. No side effects that I’ve noticed. Will continue using and highly recommend
Rated 5 out of 5

Pat M. – September 18, 2018

Less knee and foot pain and swelling since started 3 mos. ago. No more meds or glucosamine. Recommend.
Rated 4 out of 5

Michael J – September 12, 2018

These bad boys make a world of difference for my joint aches and stiffness. Little spicy aftertaste, probably from the Curcumin but still worth the money imo
Rated 5 out of 5

Jennifer C – August 30, 2018

I could surprisingly feel less muscle and joint pain in just days of using Joint Edge Rx! Very impressed with the results I got
Rated 5 out of 5

Jose H – August 23, 2018

I’ve been doing CrossFit and suffering joint pain for years. I’ve been using Joint Edge for a couple months and let’s just say, I’m never going back. Phenomenal product!
Rated 5 out of 5

Katie W – August 16, 2018

Joint Edge is freakin amazing!! Has helped so much with my joint pain and has allowed me to get the most out of my workouts!
Rated 5 out of 5

Frank B – July 19, 2018

Thought this product was too good to be true but you guys proved me wrong. Stocking up on Joint Edge and telling all my fellow CrossFitters!
Rated 5 out of 5

Todd L – July 17, 2018

finished my first bottle yesterday and I’m very impressed. Really helped with my tenditnitis and just felt better overall while being on Joint Edge. After reading the science behind it, I wasn’t all that surprised with the results!
Rated 5 out of 5

Mark D – July 14, 2018

I’ve had joint issues for decades and tried almost everything. Joint Edge Rx has made such a huge difference in my recovery and day to day activities. It even helped with my gut health! Great work guys!!
Rated 5 out of 5

David – June 29, 2018

Can honestly say this product has proven me wrong. Was skeptical at first and now a total believer. Has truly helped me with pain and aches, have tired other products but none have work to this caliber!!!!! Truly surprised!!!
Rated 5 out of 5

Sarah K – June 28, 2018

Works so much better than the other joint health supplements I’ve tried and believe me, I’ve tried them all… So glad I found this!
Rated 5 out of 5

Brad J – June 19, 2018

I’ve been taking Joint Edge for just over a month and I must say, I’m a believer! Not only has this helped with my knee pain and stiffness but even my flexibility. Well done LionEdge!
Rated 5 out of 5

Ben W – June 8, 2018

I’ve had chronic joint pain for years and Joint Edge helped immensely. Even my orthopedic doctor was impressed with this product and started using it! Already ordered a few more for myself and friends!

Inflammation RX reviews

66 Reviews

Brenda C – February 03, 2022

Suffer from chronic knee pain in both knees for decades and I also have IBS. Ive tried almost everything and this product has really helped for both of these issues. I love that it’s all natural vegan and made by doctors. I even told my family doctor about it and she’s also referred it to some of her patients!

Alexander L – May 18, 2022

I’ve been dealing with chronic gout for years and sometimes my joints and toes swell up like balloons during my flare ups. I’ve been taking prescription medicine for quite some time but decided to give this a try after hearing about it and reading all the positive reviews and getting an ok from my doctor to use it. I can say it worked wonders for me and have less pain and even swelling during my flare ups!

See All Reviews | Add Your Review

JOINT HEALTH

Are you tired from the aches, pain and stiffness from sore joints and muscles? The ingredients in INFLAMMATION Rx have been clinically shown to help reduce inflammation, muscle pain and soreness as well as joint pain and stiffness, allowing you to recover faster and to workout longer and stronger. Stop the pain today so you can enjoy more flexibility and mobility and get back to the daily activities you love!

In patients with chronic arthritis, whether it is degenerative joint disease (osteoarthritis) or autoimmune arthritis (Rheumatoid, Lupus, Gout, Psoriasis, etc), INFLAMMATION Rx may serve as an effective and natural adjunct treatment in addition to your prescribed medications.*

GUT HEALTH

Did you know that over 75% of your immune system is in your gut? This formula will help optimize your body’s immunity and total wellness from the inside out by promoting smooth, optimal daily digestion and efficient nutrition absorption.

Immunity

INFLAMMATION Rx is fortified with vitamin C and zinc to help prevent sickness, reduce the severity of illness and to help promote recuperation. While there are countless immune boosters on the market, vitamin C and zinc are the most supported by research and are even used in treatment for coronavirus patients in many hospitals nationwide. You will also have a natural boost in antioxidants to fight free radicals and detoxification to help strengthen you immune function.

Absorption

It’s one thing to consume nutrients, it’s another for your body to effecively absorb and use them. In fact, as low as 5-20% of the nutrients you orally ingest from food or supplements will enter your systemic circulation. BioPerine® is the only patented piperine from black pepper extract to have undergone several clinical studies in the U.S. to substantiate its safety and efficacy. Bioavailability of Curcumin when co-administered with 20mg BioPerine® is enhanced by 20-fold or 2000% compared to bioavailability of Curcumin alone, vitamin C by 52% and Selenium by 43%.

Physician Formulated

Physician formulated and backed by over 10 board certified, practicing physicians, the 8 fully disclosed ingredients in INFLAMMATION Rx are maximally and clinically dosed to work synergistically together for the best results possible. Supplement with confidence knowing that every ingredient selected by our team of healthcare professionals are carefully dosed for safety and effectiveness. INFLAMMATION Rx is the result of unparalleled science, research and strict quality control standards that makes us stand apart from the competition.

Vegan Friendly

Made with non-GMO vegan friendly ingredients, this powerful natural formula can help plant based dieters combat bloating, gas, and indigestion which can sometimes accompany vegan diets.

$49.99Read more

Inflammation Rx

NATURAL ANTI-INFLAMMATORY

Additional information

Supplement Facts

Supplement Facts

Product Label

Directions

Ingredients

66 reviews for Inflammation Rx

Inflammation RX reviews

JOINT HEALTH

GUT HEALTH

Immunity

Absorption

Physician Formulated

Vegan Friendly

JOIN LIONEDGE

Who We ARe

SUPPORT

Contact Us